Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function
نویسندگان
چکیده
منابع مشابه
Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function.
Inhalation of iloprost, a stable prostacyclin (PGI(2)) analog, is a well-accepted and safe treatment for pulmonary arterial hypertension. Although iloprost mainly acts as a vasodilator by binding to the I prostanoid (IP) receptor, recent evidence suggests that signaling via this receptor also has antiinflammatory effects through unclear mechanisms. Here we show in a murine model of asthma that ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2007
ISSN: 0021-9738
DOI: 10.1172/jci28949